Molecular Silk Amino Hydrating Cleanser. Allies of Skin. Official Stockist. Worldwide shipping. Medical-grade skincare. The M-ethod Aesthetics

Polynucleotides

From:

£350.00

Polynucleotides deliver advanced biostimulatory injections that activate dermal collagen synthesis, effectively reversing skin laxity for a firmer, lifted complexion. At The M-ethod Skin Clinic, Dr. Mandy Mak offers the complete Plinest® lineup, tailored for superior rejuvenation.

Discover Polynucleotides

These advanced biostimulatory injections activate collagen and elastin synthesis within the skin’s dermis, effectively diminishing fine lines, enhancing plumpness, and countering visible aging. Dr. Mandy Mak at The M-ethod Skin Clinic offers the full Plinest® range, with targeted scalp application also available to improve circulation and promote hair growth over time.

How Polynucleotides work

Polynucleotides consist of long-chain, high molecular weight molecules that activate dermal fibroblasts, driving elevated collagen and elastin synthesis for structural renewal. Their exceptional viscoelastic properties ensure the skin swiftly regains its natural resilience and bounce. Administered via precise multi-point injections in the treatment zone, the formula disperses evenly across the dermis—similar to Profhilo—for comprehensive rejuvenation.

Polynucleotides Benefits

Polynucleotides deliver profound dermal hydration while smoothing fine lines and wrinkles, elevating collagen and elastin production for progressive tissue remodeling. Expect a radiant, resilient complexion with enhanced elasticity, vitality, and luminous glow.

Treatment Areas with Polynucleotides

Polynucleotides effectively address skin concerns across the body, with the face and neck as the most sought-after zones. Dr. Mandy Mak offers Plinest® Eyes specifically for the delicate eye area, targeting laxity and crepiness for a smoother, firmer result. Scalp treatments with Plinest® also promote healthier circulation, potentially enhancing hair growth over time.

Can Polynucleotides be combined with other treatments?

Polynucleotides integrate seamlessly with complementary therapies, including anti-wrinkle injections, dermal fillers, and routine facials, to amplify rejuvenation results under Dr. Mandy Mak’s expert guidance.

What is the downtime with Polynucleotides?

Polynucleotides involve minimal downtime, varying by treatment area, with small raised bumps at injection sites typically resolving within hours. Mild bruising or swelling may occur—as with any injectables—and is more common under the eyes; to minimize risks, Dr. Mandy Mak recommends avoiding omega-3 supplements, blood thinners, and alcohol for 48 hours beforehand.

Polynucleotides

£350.00

TREATMENT TIME

15 min

Discomfort Level

1 out of 5

Downtime

Minimal, varies based on area.

results seen in

2-3 sessions, 4-6 weeks apart.

Need assistance?

FAQs

This FAQ section addresses essential questions about polynucleotides. Dr. Mandy will provide comprehensive, personalized protocols during your consultation and treatment.

What are polynucleotides, and how do they differ from other injectables?

Polynucleotides are exquisitely purified, high-molecular-weight DNA chains derived from salmon and refined for optimal human affinity, functioning as elite biostimulators to orchestrate deep cellular repair and regeneration—distinct from volume-adding fillers or muscle-relaxing neurotoxins.

Am I a good candidate for Plinest® polynucleotides at The M-ethod Skin Clinic?

Perfect for discerning clients pursuing refined natural rejuvenation against early aging, laxity, or dullness, across diverse skin types; Dr. Mandy Mak conducts a bespoke consultation to affirm suitability and elevate your radiant transformation.

How many sessions will I need, and how long do results last?

An elegant protocol of 2-3 sessions, spaced 4-6 weeks apart, with maintenance every 6-12 months, unveils progressive collagen vitality and luminous elasticity for enduring, sophisticated outcomes.

Does the treatment hurt, and is anesthesia used?

Expect mild prickling from fine-needle injections, akin to other biostimulants; Dr. Mandy Mak applies topical numbing cream 20-30 minutes prior for enhanced comfort, particularly in sensitive areas like the eyes or scalp.

What results can I expect after polynucleotides?

Immediate hydration and subtle radiance emerge within days, culminating in supremely firm, line-softened, velvety texture over 4-6 weeks as fibroblasts awaken—bestowing a holiday-ready resilient glow.

Are there side effects or risks?

Side effects remain minimal and mild: temporary redness, swelling, or small bumps typically fade within hours to days; bruising is uncommon, managed effectively through Dr. Mandy Mak’s precise pre- and post-care protocols.

How should I prepare for and after my appointment?

Avoid blood thinners, alcohol, and omega-3 supplements 48 hours before treatment; afterward, prioritize hydration and gentle skincare while skipping makeup, direct sun exposure, and heat sources for 24-48 hours—ideal for seamless vacation enhancement in Athens. Dr. Mandy Mak provides a personalized at-home protocol following each session for optimal results.